ISSN print edition: 0366-6352
ISSN electronic edition: 1336-9075
Registr. No.: MK SR 9/7
Electrochemical investigations of thymine and thymidine in 1-butyl-3-methyl imidazolium tetrafluoroborate ionic liquids at room temperature
Shivaji Tayade, Kiran Patil, Geeta Sharma, Pramod Patil, Rahul M. Mane, Pramod Mahulikar, and Kiran Kumar K. Sharma
Shivaji University, Kolhapur, India
Abstract: The electrochemical reduction of thymine (T) and thymidine (Thy) in 1-butyl-3-methylimidazolium tetrafluoroborate ionic liquid at room temperature is investigated using cyclic voltammetry (CV). The CV of thymine shows one-electron reduction peak at − 0.67 V vs Fc/Fc+, while thymidine exhibited two reduction peaks corresponding to − 1.54 V and at − 2.06 V vs Fc/Fc+. The difference in the reduction peaks of thymine and thymidine observed suggests a single-step and two-step reductions, respectively. The experimental voltammogram was convoluted for the the estimation of diffusion coefficient, charge transfer coefficient, kinetics, and energetics of thymine and thymidine. The theoretical prediction using semi-integral technique suggests that thymidine at the reduction peak − 1.54 V vs Fc/Fc+ proceeds a one-electron reductive cleavage of N–C glycosidic bond (nitrogen–carbon) via concerted dissociative electron-transfer mechanism while thymine.
Keywords: Ionic liquids ; Thymine ; Thymidine ; Convolution ; Concerted dissociative electron transfer ; Marcus theory
Full paper is available at www.springerlink.com.
Chemical Papers 73 (9) 2275–2282 (2019)
Monday, September 26, 2022