ISSN print edition: 0366-6352
ISSN electronic edition: 1336-9075
Registr. No.: MK SR 9/7
Aerobic oxidative conversion of benzylic alcohols with ammonia to nitriles catalyzed by CuCl/TEMPO/PIC
Longfei Yuan, Guohui Yin, Hong-yu Zhang, Yuecheng Zhang, and Jiquan Zhao
Hebei University of Technology, Tianjin, China
Abstract: A catalyst system consisting of copper (I) chloride, sodium 2-picolinate (PIC) and TEMPO has been found to be effective in the aerobic oxidative conversion of benzylic alcohols with aqueous ammonia to nitriles in the absence of organic solvent. Various benzyl alcohols were converted to their corresponding nitriles in high yields. The ligand PIC can be easily removed from the reaction mixture due to its water solubility, allowing for easy product purification.
Keywords: Alcohols ; Aerobic oxidation ; Nitriles ; Copper (I) chloride ; Sodium 2-picolinate
Full paper is available at www.springerlink.com.
Chemical Papers 72 (10) 2679–2685 (2018)