ISSN print edition: 0366-6352
ISSN electronic edition: 1336-9075
Registr. No.: MK SR 9/7
Preparation, spectral, thermal, and biological properties of zinc(II) 4-chloro- and 5-chlorosalicylate complexes with methyl 3-pyridylcarbamate and phenazone
Zuzana Bujdošová, Katarína Györyová, Daniela Hudecová, Jana Kovářová, and Ladislav Halás
Department of Inorganic Chemistry, P. J. Šafárik University, Moyzesova 11, 041 54 Košice, Slovakia
Abstract: New zinc(II) 4-chloro- and 5-chlorosalicylate complex compounds of the general formula ((4- or 5-Cl)C6H3(2-OH)COO)2Zn · L
(where L = methyl 3-pyridylcarbamate, phenazone; n = 2, 4) were prepared and characterized by elemental analysis, thermal analysis (TG/DTG, DTA), and IR spectroscopy. During
thermal decomposition, mpc, phen, chlorosalicylic acid, chlorophenol, carbon dioxide, and carbon monoxide were released. Volatile
products of the thermal decomposition were confirmed by mass spectrometry. The final solid product of the thermal decomposition
up to 700°C was zinc oxide or metallic zinc. Antimicrobial activity of the compounds prepared was tested against various strains
of bacteria, yeasts and filamentous fungi. The highest antimicrobial effect was determined against the G+ bacteria S. aureus.
Keywords: methyl 3-pyridylcarbamate - phenazone - zinc(II) chlorosalicylate - thermal and biological properties - IR spectra
Full paper is available at www.springerlink.com.
Chemical Papers 64 (5) 584–591 (2010)
Monday, September 26, 2022