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Esters of o-dimethylaminocyclohexanols

L. Dúbravková, I. Ježo, P. Šefčovič, and Z. Votický

Slovak Academy of Sciences, Bratislava

 

Abstract: The following esters of o-dimethylaminocyclohexanol with aliphatic and aromatic acids were prepd. (acid, b.p./mm. and % yield of ester, and m.p. of hemi-H2PtCl6 salt of ester given): AcOH, 95-7°/14, 69, 113-15°; EtCO2H, 112-14°/15, 74, 136-8°; iso-PrCO2H, 127-9°/12, 75, 127-9°; m-MeOC6H4CO2H, -, 50, 110-12°; 3,4-(MeO)2C6H3CO2H, -, 58, 123-5°; 3,4,5-(MeO)3C6H2CO2H, -, 56, 132-4°. Their hypotensive properties were studied.

Full paper in Portable Document Format: 113a150.pdf (in Slovak)

 

Chemical Papers 11 (3) 150–152 (1957)

Wednesday, September 30, 2020

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