ISSN print edition: 0366-6352
ISSN electronic edition: 1336-9075
Registr. No.: MK SR 9/7
New Cu(II), Co(II), and Ni(II) complexes with thieno[2,3-
]pyridine and 2-methylthieno[2,3-
]pyridine as ligands: Synthesis and crystal structures
Ján Halgaš, Viera Kolenová, Zuzana Števíková, Lucia Perašínová, and Jozef Kožíšek
Department of Chemistry, University of Ss. Cyril and Methodius, J. Herdu 2, 917 01 Trnava, Slovakia
Received: 10 April 2008 Revised: 22 September 2008 Accepted: 24 September 2008
Abstract: Although thienopyridines attract attention because of their biological activities, they have not been used as ligands in coordination
compounds. Thieno[2,3-b]pyridine was prepared by known procedures; by reduction of 2-nitrothiophene, and reaction of the resulting 2-thienyl ammonium
salt with malondialdehyde tetramethylacetal in the presence of zinc chloride. The same procedure was used for the preparation
of a new derivative, 2-methylthieno[2,3-b]pyridine, starting from 2-methyl-5-nitrothiophene. The thienopyridines were used in the synthesis of coordination compounds.
Chlorides, isothiocyanates, acetates, and chloroacetates of copper(II), nickel(II), or cobalt(II) were used as starting salts.
The prepared complexes were characterized by elemental analysis and FT IR. Structures of the four complexes were determined
by single-crystal X-ray diffraction analysis.
Keywords: thieno[2,3-b]pyridine - 2-methylthieno[2,3-b]pyridine - ligands - coordination compounds - X-ray structures
Full paper is available at www.springerlink.com.
Chemical Papers 63 (3) 323–328 (2009)