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Benzothiazole compounds. I. Synthesis and antimicrobial investigation of 6-substituted allyl(2-benzothiazolylthio)acetates

V. Sutoris, P. Foltínová, and G. Blőckinger

Department of Organic Chemistry and Biochemistry, Faculty of Natural Sciences, Komenský University, 801 00 Bratislava

 

Abstract: Allyl (6-X-2-benzothiazolylthio)acetates (X = H, N02 , NH2, CI, Br, NHR. N(R)2; R = CH3, C2H5, CH2CH = CH2, СН2С=СН) were synthesized and their antimicrobial efficiencies studied. Some derivatives (X = H, N02, NH2, Br) showed significant positive microbiological effect. Alky lat ion of the amino group resulted in a decrease of the antimicrobial efficiency.

Full paper in Portable Document Format: 275a698.pdf

 

Chemical Papers 27 (5) 698–702 (1973)

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