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Benzothiazole compounds. XVI. Preparation and antimycobacterial activity of N',N'-bis[(2-thioxo-3-benzothiazolinyl)methyl]hydrazides

E. Holbová and Ž. Odlerová

Institute of Chemistry, Komenský University, 816 50 Bratislava

 

Abstract:  The reaction of 2-mercaptobenzothiazole with formaldehyde and hydrazides of acids resulted in bis derivatives of Mannich bases. The relationship between the formation of bis derivatives and the a effect in hydrazides is explained. The prepared compounds were tested for antimycobacterial activity.

Full paper in Portable Document Format: 343a399.pdf

 

Chemical Papers 34 (3) 399–403 (1980)

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