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Benzothiazole compounds. XVII. Preparation and biological activity of Mannich bases with 2-benzothiazolinone

V. Sutoris, M. Šušoliaková, E. Holbová, and B. Rada

Department of Organic Chemistry, Faculty of Natural Sciences, Komenský University, 816 31 Bratislava

 

Abstract:  Reaction of 2-benzothiazolinone with formaldehyde and primary amines leads to formation of mono or bis derivatives. Reaction of 2-benzothiazolinone with formaldehyde and secondary amines is also described. Position of the substituents on 2-benzothiazolinone was established by ultraviolet and infrared spectroscopy. It has been found that the prepared compounds are less effective against mycobacteria and viruses than the corresponding derivatives of 2-benzothiazolinethione.

Full paper in Portable Document Format: 345a700.pdf

 

Chemical Papers 34 (5) 700–705 (1980)

Thursday, June 13, 2024

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