ISSN print edition: 0366-6352 ISSN electronic edition: 1336-9075 Registr. No.: MK SR 9/7 Published monthly

New complexanes. XLI. Study of equilibriums of the chelate formation of N-(carbamoylmethyl)iminodiacetic and N-(2-carbamoylethyl)iminodiacetic acids with cations of the alkaline earth metals

I. Benedikovič, P. Balgavý, P. Novomeský, E. Fűleová, E. Riečanská, A. Topanou, and J. Majer

Department of Analytical Chemistry, Faculty of Pharmacy, Komenský University, 88034 Bratislava

Abstract: The relative thermodn. acid-base equil. and equil. of the complex formation of N-(carbamoylmethyl)iminodiacetic and N-(2-carbamoylethyl)iminodiacetic acid with Mg(II), Ca(II), Sr(II), and Ba(II) were studied by direct potentiometric neutralization titrn. under unified conditions (I = 0.1 KNO₃) and at 15, 20, 25, 30 and 35°. The resulting values of ΔH° and ΔS° are given for the protonation equil. and equil. of the complex formation with the above cations. The formation of these complexes was also studied by ¹H-N.M.R. spectroscopy in D₂O solns. in the pD range 1.5-13.0. The results are discussed from the view-point of formation of a coordination bond between the amide group and central metal in a complex of the ML type.

Full paper in Portable Document Format: 345a630.pdf

Chemical Papers 34 (5) 630–636 (1980)