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Extraction of quaternary ammonium salts of heptacaine

M. Pešák, L. Šlechtová, J. Čižmárik, A. Borovanský, and P. Švec

Department of Physical Chemistry, Faculty of Pharmacy, Komenský University, CS-832 32 Bratislava

 

Abstract:  The paper deals with the transition of some local anaesthetically active quaternary ammonium salts of heptacaine from aqueous phase into octanol in the form of ion pairs. The dependence of the extraction constants on the size of an alkyl substituent is followed and the electronic spectra of the studied compounds are presented.

Full paper in Portable Document Format: 372a237.pdf

 

Chemical Papers 37 (2) 237–242 (1983)

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