ISSN print edition: 0366-6352
ISSN electronic edition: 1336-9075
Registr. No.: MK SR 9/7

Published monthly
 

Synthesis, spectral properties, and IRH of 2,4,5-trisubstituted 3-oxo-2H-pyridazines

V. Konečný, Š. Kováč, and Š. Varkonda

Research Institute of Chemical Technology, CS-831 06 Bratislav

 

Abstract: The synthesis of 2-R2-4-alkoxy-5-chloro-, 2-R2-5-alkoxy-4-chloro-, and 2-R2-4,5-dialkoxy-3-oxo-2H-pyridazines by the reaction of 2-R2-4,5-di- chloro- or 2-R2-4-chloro-5-alkoxy or 2-R2-5-alkoxy-4-chloro-3-oxo-2H- -pyridazines with sodium alcoholate or alcohol in the presence of alkaline carbonate in aprotic or protic solvent is described. Infrared and ultraviolet spectra of the prepared compounds are interpreted. Prepared compounds were tested for fungicidal and herbicidal activity. In fungicidal activity none of the prepared compounds reached the activity of the standard Vitavax, in the inhibiting of the Hill reaction 2-cyclohexyl-4-methoxy-5-chloro-2-(3' -methylphenyl)-4-methoxy-5-chloro-, 2-(3'-chlorophenyl)-4-methoxy-5-chloro-, 2-cyclohexyl-4-chloro-5-methoxy-, 2-phenyl-4-chloro-5-methoxy-,2-(3'- chlorophenyl)-4-chIoro-5-methoxy-, 2-phenyl-4,5-dimethoxy-, 2-(3'-trifluoro- methylphenyl)-4,5-dimethoxy-3-oxo-2H-pyridazines reached or surpassed the activity of the standard Pyrazon.

Full paper in Portable Document Format: 394a513.pdf

 

Chemical Papers 39 (4) 513–526 (1985)

Thursday, September 23, 2021

IMPACT FACTOR 2020
2.097
SCImago Journal Rank 2020
0.344
SEARCH
Advanced
VOLUMES
XXVIII. International Conference on Coordination and Bioinorganic Chemistry
© 2021 Chemical Papers