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Bead cellulose and its use in biochemistry and biotechnology

P. Gemeiner, M.J. Beneš, and J. Štamberg

Institute of Chemistry, Centre for Chemical Research, Slovak Academy of Sciences, CS-84238 Bratislava


Abstract: In recent years, the significance of granular insoluble polymers, the action of which is based on interaction between their own functional groups and the compounds dissolved in the medium, has increased also in biochemistry and biotechnology. The so-called functional polymers are most frequently used as carriers of active compounds or groups, separation media, catalysts, adsorbents, etc. In biochemical systems, hydrophilic polymers with expedient physical micro- and macrostructures have special significance with regard to the interacting substrates, particularly their mass, and to formation of optimal conditions for the interaction itself. Insoluble polysaccharides with porous structure and spherical shape of particles attract an extraordinary attention. Cellulose has often been used as a carrier of functions in biochemistry, first of all due to its availability and good chemical reactivity. However, low porosity and nonspherical shape of the individual particles impeded its wider application. These disadvantages are eliminated with bead porous cellulose, prepared lately [1-4].

Full paper in Portable Document Format: 436a805.pdf


Chemical Papers 43 (6) 805–848 (1989)

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