ISSN print edition: 0366-6352
ISSN electronic edition: 1336-9075
Registr. No.: MK SR 9/7

Published monthly
 

Preparation of 2-acetamido-2-deoxy-β-D-glucopyranosyl-methylamine via nitromethane route

M. Petrušová, M. Fedoroňko, and L. Petruš

Institute of Chemistry, Centre for Chemical Research, Slovak Academy of Sciences, CS-842 38 Bratislava

 

Abstract: Epimeric 3-acetamido-l,3-dideoxy-l-nitroheptitols formed in the ni­tromethane synthesis with N-acetyl-D-glucosamine were converted to 2-acetamido-2-deoxy-β-D-glucopyranosylnitromethane by intramolecular cyclodehydraiion. The compound was isolated as a salt of a strongly basic anion-exchange resin in the OH form, from which it was liberated by carbon dioxide. Reduction of the nitro derivative with iron(II) hydroxide in situ afforded 2-acetamido-2-deoxy-β-D-glucopyranosylmethylamine. Its struc­ture was proved by the , 13C NMR spectrometry.

Full paper in Portable Document Format: 442a267.pdf

 

Chemical Papers 44 (2) 267–271 (1990)

Friday, October 18, 2019

IMPACT FACTOR 2018
1.246
SCImago Journal Rank 2018
0.274
SEARCH
Advanced
VOLUMES
International Conference on Coordination and Bioinorganic Chemistry
46th International Conference of SSCHE
© 2019 Chemical Papers