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Reactions of Methyl Derivatives of 2-Penten-5-olide, 2-Buten-4-olide, and Coumarin with Dicarboxylic Anhydrides and with 3-Formylchromones under the Perkin Synthesis Conditions

G. S. Melikyan, M. Lácová, K. Kráľová, H. M. Elshaaer, M. Henselová, and A. A. Avetisyan

Department of Organic Chemistry, Faculty of Chemistry, Yerevan State University, 375 049 Yerevan

 

Abstract: 4H-4-Oxo-3-(R-vinylene)chromene derivatives and 3-(R-methylene)phthalide derivatives have been prepared by condensation reactions (R = 2H,5H-2-oxo-5,5-dimethyl-3-R5-4-furyl; 2H-2-oxo-6-dimethyl-3-R5-5,6-dihydropyran-4-yl; 2H-2-oxo-3-R5-4-chromenyl; R5 = CN, CONH2, CO2C2H5,[GRAPHICS].Some of the prepared compounds were tested for a variety of biological activities (for herbicidal, fungicidal, growTh-regulating activity, for antifungal activity against human pathogenic dermatophytes and micromycetes, and also for their possible anti-HIV activity).

Full paper in Portable Document Format: 476a388.pdf

 

Chemical Papers 47 (6) 388–392 (1993)

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