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Synthesis and Antibacterial Properties of 7β-[2-(3-Heteroarylthiazolo[2,3-c]-s-triazol-5-yl)- acetamido]cephalosporanic Acid Derivatives

M. Veverka

Drug Research lnstitute,SK-900 01 Modra

 

Abstract: A series of 7 β-[2-(3-heteroarylthiazolo[2,3-c]-s-triazol-5-yl)acetamido]cephalosporanic acid derivatives were synthesized and evaluated microbially. Although less active than cefotaxime, the compounds having thiazolo[2,3-c]-s-triazole ring showed good antimicrobial activity against a wide variety of gram-positive and gram-negative bacteria.

Full paper in Portable Document Format: 482a111.pdf

 

Chemical Papers 48 (2) 111–113 (1994)

Tuesday, March 19, 2024

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