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Separation of Derivatives of l-(2-Hydroxypropyl)-2-methyl-5-nitroimidazole by Capillary Zone Electrophoresis

B. Proksa, M. Koóš, and B. Steiner

Slovakofarma, a.s., SK-920 21 Hlohovec

 

Abstract: Chiral derivatives of 1-(2-hydroxypropyl)-2-methyl-5-nitroimidazole substituted on the 2-hydroxypropyl chain were separated by capillary zone electrophoresis; the effect of background electrolyte concentration and addition of cyclodextrins and achiral pairing reagent were studied. The best resolution was observed with compound having thiophenyl substituent attached to the aliphatic moiety.

Full paper in Portable Document Format: 515a276.pdf

 

Chemical Papers 51 (5) 276–279 (1997)

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