ISSN print edition: 0366-6352
ISSN electronic edition: 1336-9075
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Synthesis of new triphenodithiazine- and indolocarbazolediones of biological interest

A. S. Hammam, M. S. K. Youssef, F. M. Atta, and Th. A. Mohamed

Department of Chemistry, Faculty of Science, Assiut University, Assiut, 71516, Egypt

 

E-mail: hammam_as@yahoo.com salah_kamel2000@yahoo.com

Received: 21 November 2006  Revised: 3 March 2007  Accepted: 7 March 2007

Abstract: Tetrabromo-p-benzoquinone reacted with excess aromatic amines to give 2,5-dirylamino-3,6-dibromo-p-benzoquinones. The latter molecules on heating with sodium sulfide in alcohol in the presence of air gave triphenodithiazinediones. Heating with copper powder in nitrobenzene transformed these compounds into the respective indolocarbazolediones. Comparative antimicrobial and antifungal activities of the studied compounds were determined and discussed.

Keywords: triphenodithiazinediones - indolocarbazolediones - synthesis - antimicrobial activity - antifungal activity

Full paper is available at www.springerlink.com.

DOI: 10.2478/s11696-007-0036-1

 

Chemical Papers 61 (4) 292–299 (2007)

Wednesday, December 11, 2024

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