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Structure-Affected Bioactivity of Triorganotin Compounds

J. Kizlink

Department of Chemistry and Environmental Technology, Faculty of Chemistry, Brno University of Technology, CZ-612 00 Brno


Abstract: The biocidal activity of 8 triorganotins R3SnX (R = butyl, phenyl, benzyl; X = oxide, chloride, acetate, naphthenate, N, N-diethyldithiocarbamate) on brown rot fungi, moulds mixture, benthic organisms, plankton alga Scenedesmus quadricauda, and crop plant has been investigated. The results suggest dependence between lipophilicity of bounded R groups and intensity of unfavourable effect. The most effective triorganotins were compounds with butyl group in n-alkyl chain, the least active were the tribenzyltins. In general, independently on the investigated biological object, the strongest biocidal activity was shown by bis(tributyltin) oxide whereas the lowest inhibitory efficiency was exhibited by tributyltin naphthenate. The effect of X group on biocidal activity was not significantly manifested.

Full paper in Portable Document Format: 551a53.pdf


Chemical Papers 55 (1) 53–57 (2001)

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