ISSN print edition: 0366-6352 ISSN electronic edition: 1336-9075 Registr. No.: MK SR 9/7 Published monthly

Synthesis of new condensed and cyclized coumarin derivatives

S. V. Dekić, V. S. Dekić, B. R. Dekić, and M. S. Dekić

Department of Chemistry, Faculty of Sciences and Mathematics, University of Priština, 38220 K. Mitrovica, Serbia

E-mail: dekic@inbox.com

Received: 15 January 2007  Revised: 1 February 2007  Accepted: 5 February 2007

Abstract: Condensation of 4-chloro-2-oxo-2H-chromene-3-carbonitrile with selected heteroarylamines in acetonitrile containing a catalytic amount of triethylamine, followed by intramolecular cyclization, gave the new coumarin derivatives with yields ranging from 43 % to 78 %. The novel compounds were subjected to acid hydrolysis giving the corresponding oxo derivatives in 66–70 % yield. The structural assignments of the synthesized compounds were based on elemental, IR, ¹H and ¹³C NMR analyses.

Keywords: coumarin derivatives - condensed rings - cyclization - acid hydrolysis - structural determination

Full paper is available at www.springerlink.com.

DOI: 10.2478/s11696-007-0027-2

Chemical Papers 61 (3) 233–235 (2007)