ISSN print edition: 0366-6352
ISSN electronic edition: 1336-9075
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Various-sized ZnO nanoformulations synthesized with both aqueous and ethanol extracts of Paederia lanuginosa leaves

Thi Thu Huong Le, Thi Bich Thuan Nguyen, Thi Hong Hanh Nguyen, Thi Thuong Ngo, and Thi Thanh Chu

Faculty of Natural Resources and Environment, Vietnam National University of Agriculture, Hanoi, Vietnam



Received: 22 January 2023  Accepted: 30 May 2023



ZnO nanoparticles (NPs) have shown high potential in various antibacterial applications. This study greenly synthesized ZnO NPs at different sizes using Paederia lanuginosa aqueous leaf extract and active compounds in Paederia lanuginosa ethanol extract were incorporated into the ZnO NPs to form different ZnO-extract nanoformulations. Chemical methods, FeSEM, UV–Vis, FTIR, EDX spectra, XRD, DLS, and TGA were used to characterize the synthesized extracts, ZnO NPs, and their nanoformulations. The results show that the ZnO NPs had the size of 20–30, 50–70, or 100–150 nm. Organic substances including phenolics, glycosides, and iridoids were present in the nanoformulations. The nanoformulations enlarge the inhibition zone of ZnO nanoparticles against E. coli ATCC 25922 and are potential for antibacterial applications.

Graphical abstract

Keywords: ZnO nanoformulations; Paederia lanuginosa extracts; Active compounds; Antibacterial activity; E. coli

Full paper is available at

DOI: 10.1007/s11696-023-02899-w


Chemical Papers 77 (10) 5817–5827 (2023)

Thursday, May 30, 2024

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