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Simplified prepared silver nanoparticles for ultra-sensitive enhanced Raman spectroscopy substrate

Shuo Zhang, Hao Jiang, Guomin Ye, Kai Xiong, Yong Mao, Peng Yang, and Yanfen Wan

Materials Genome Institute, Advanced Computing Center, School of Materials and Energy, Yunnan University, Kunming, People’s Republic of China



Received: 16 May 2022  Accepted: 10 November 2022


Rapidly nondestructive detection technologies play an essential role in industry of food, petro-chemical and aerospace. Herein, assembled Ag nanoparticles with average diameter of 67 nm were successfully fabricated as an active SERS substrate through a modified polyol method. Rhodamine 6G (R6G, target–molecular) and Ag NPs were mixed directly, achieving an ultra-high sensitive SERS substrate with a high R6G limiting resolution of 10−12 and a superior Enhancement Factor (EF) up to 2.2 × 109. Besides, the uniformity of R6G’s Raman intensity was demonstrated, which implies that the substrate emerges a potential value in the areas of medicine, food safety and biotechnology.

Keywords: Briefly synthesized Ag NPs; Trace molecule detection; Raman signal's attenuation model

Full paper is available at

DOI: 10.1007/s11696-022-02589-z


Chemical Papers 77 (3) 1713–1720 (2023)

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