ISSN print edition: 0366-6352
ISSN electronic edition: 1336-9075
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Efficacy of postbiotics against free radicals and UV radiation

Aneta Ácsová, Jarmila Hojerová, and Silvia Martiniaková

Department of Food Technology, Institute of Food Science and Nutrition, Faculty of Chemical and Food Technology, Slovak University of Technology in Bratislava, Bratislava, Slovakia



Received: 10 July 2021  Accepted: 13 December 2021


The importance of probiotics for the internal and external human microbiota has already been scientifically confirmed. As these are viable bacteria, the direct dermal use of them through mass-produced cosmetics is impossible. For these purposes, postbiotics—substances derived from probiotics through fermentation processes—appear to be promising. Two postbiotics have been investigated in vitro for their protective ability against free radicals and UV radiation compared to conventional synthetic chemicals. Lactococcus Ferment Lysate and Bifida Ferment Lysate in 5% aqueous solution and 100% concentrate were able to scavenge from 0.15 to 54.2% and 7.0 to 71.0%, respectively, of 2,2-diphenyl-1-picrylhydrazyl radical. L. Ferment Lysate in the emulsion, the composition of which is a reference in testing the effectiveness of sunscreen products with a low SPF value, showed an absorption capacity in the UVB region (SPF 4.75) comparable to the standard chemical UV filter Homomenthyl salicylate (SPF value of 4.45) and in the UVA region better than this standard. The UV absorption ability of B. Ferment Lysate was negligible. Postbiotics B. Ferment Lysate and L. Ferment Lysate are beneficial natural active ingredients for the skin protection against free radicals and L. Ferment Lysate also against UVB + UVA radiation.

Keywords: Probiotic ferment lysate; Postbiotic; Spectrophotometry; Free radical scavengers; Photoprotectives

Full paper is available at

DOI: 10.1007/s11696-021-02018-7


Chemical Papers 76 (4) 2357–2364 (2022)

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