ISSN print edition: 0366-6352
ISSN electronic edition: 1336-9075
Registr. No.: MK SR 9/7

Published monthly
 

Synthesis and characterization of new benzyl-protected 2-iodo-4-tert-octylphenol and its application in preparation of 1-benzyloxy-2-(3,6-di-tert-butyl-9H-carbazolyl)-4-tert-octylbenzene

Yong-Qing Li, Luo-Yi Wang, Quan-chao Wang, Yu-Cai Hu, Yu-Chen Ci, and Yu-Cai Cao

State Key Laboratory of Polyolefins and Catalysis, Shanghai Key Laboratory of Catalysis Technology for Polyolefins, Shanghai Research Institute of Chemical Industry Co. Ltd., Shanghai, People’s Republic of China

 

E-mail: caoyc@srici.cn

Received: 26 July 2021  Accepted: 9 September 2021

Abstract:

1-Benzyloxy-2-iodo-4-tert-octylbenzene was synthesized with new methods from 4-tert-octylphenol via bromination, benzyl protection and halogen exchange reaction. Improved yield and easy purification benefit this method. The effects of solvents and ligands in halogen exchange reaction were studied in detail. The synthesized 1-benzyloxy-2-iodo-4-tert-octylbenzene was further examined for its application in Ullmann coupling reaction for preparation of 1-benzyloxy-2-(3,6-di-tert-butyl-9H-carbazolyl)-4-tert-octylbenzene. These newly synthesized compounds were characterized by IR, GC, 1H NMR, 13C NMR, GC–MS and HRMS.

Keywords: Non-metallocene; Halogen exchange; Benzyl protection; Recrystallization

Full paper is available at www.springerlink.com.

DOI: 10.1007/s11696-021-01867-6

 

Chemical Papers 76 (1) 287–292 (2022)

Tuesday, November 29, 2022

IMPACT FACTOR 2021
2.146
SCImago Journal Rank 2021
0.365
SEARCH
Advanced
VOLUMES
European Symposium on Analytical Spectrometry ESAS 2022
© 2022 Chemical Papers