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A thiamonomethinecyanine probe for detection of Pb2+ based on transformation from dimer to monomer by aptamer

Li-Jia Yu, Han Zhao, Ying-Lin Zhang, Xiao-Dong Shi, and Chun-Guang Ding

National Center for Occupational Safety and Health, NHC, Beijing, China

 

E-mail: yulijia@iccas.ac.cn

Received: 21 June 2020  Accepted: 12 October 2020

Abstract:

A simple method based on a thiamonomethinecyanine dye (dye2) and duplex DNA system was constructed to detect Pb2+ by UV–Vis spectra. The absorption spectra of dye2 show dimers and monomers peak and the monomer–dimer equilibrium could be regulated with environmental change. Duplex DNA as a template was used to regulate distinct aggregates of cyanine dye in the presence of Pb2+. This system shows a specific absorption signal for Pb2+ detection.

Keywords: Thiamonomethinecyanine dye; Pb2+ detection; Dimers and monomers; Assembly and disassembly; G-quadruplex

Full paper is available at www.springerlink.com.

DOI: 10.1007/s11696-020-01389-7

 

Chemical Papers 75 (4) 1413–1419 (2021)

Sunday, April 21, 2024

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