ISSN print edition: 0366-6352
ISSN electronic edition: 1336-9075
Registr. No.: MK SR 9/7
Photodynamic efficiency of porphyrins encapsulated in polysilsesquioxanes
Renata Rychtáriková, Stanislav Šabata, Jiří Hetflejš, and Gabriela Kuncová
Department of Organic Synthesis and Analytical Chemistry, Institute of Chemical Process Fundamentals of the AS CR, CZ-165 02 Prague 6 — Suchdol, Czech Republic
Abstract: Mesoporous organosilica-porphyrin composites were obtained by entrapment of 5,10,15,20-tetraphenylporphyrin (TPP) and 5,10,15,20-tetrakis(1-methyl-4-pyridinio)porphyrin
(TMPyP) into three polysilsesquioxanes prepared by the sol-gel method from 1,2-bis(triethoxysilyl)ethane, 1,6-bis(triethoxysilyl)hexane,
and 1,8-bis(triethoxysilyl)octane. The materials were characterised by their texture and optical properties (fluorescence
and absorbance) and by light-induced antimicrobial activity against E. coli BL21(DE3) (pET16bDsRed) strain.
Keywords: porphyrin – immobilisation – specific surface area – absorbance – fluorescence – bacteria – photoinactivation
Full paper is available at www.springerlink.com.
Chemical Papers 66 (4) 269–277 (2012)