ISSN print edition: 0366-6352 ISSN electronic edition: 1336-9075 Registr. No.: MK SR 9/7 Published monthly

Palladium/phosphoramidite-selenide-catalyzed enantioselective allylic amination

Bin Feng, Yuan-Cheng Li, Tang-Ling Hou, Cui-Zhen Wang, Hong-Kai Huang, and Ge-Yun You

Guangxi Key Laboratory of Urban Water Environment, College of Chemistry and Environmental Engineering, Baise University, Baise, China

E-mail: yougeyun1988@163.com

Received: 1 October 2025  Accepted: 30 December 2025

Abstract:

Herein, we report an enantioselective Pd-catalyzed allylic amination reaction using phosphoramidite-selenide ligands. A wide variety of N-nucleophiles are suitable in this reaction, furnishing corresponding allylic amination products in up to 93% yield and 90% ee.

Keywords: Asymmetric catalysis; Chiral selenide ligands; Allylic amination; Palladium

Full paper is available at www.springerlink.com.

DOI: 10.1007/s11696-025-04636-x

Chemical Papers 80 (3) 3207–3211 (2026)