ISSN print edition: 0366-6352 ISSN electronic edition: 1336-9075 Registr. No.: MK SR 9/7 Published monthly

Neem (Azadirachta indica) leaf extract-based green route to reduced graphene oxide towards reduction of oximes into amines

Bhushashi Khuntey, Devkumari Patel, Smriti Suryavanshi, Sanju Yadav, Ankita Rai, Manorama Singh, and Vijai K. Rai

Department of Chemistry, Guru Ghasidas Vishwavidyalaya, Bilaspur, India

E-mail: vijaikrai@hotmail.com

Received: 21 September 2025  Accepted: 7 December 2025

Abstract:

Herein, we report Neem-leaf extract-induced reduction of graphene oxide and its novel application towards catalytic reduction of oximes to corresponding amines. The reduction of graphene oxide is expedient, cost-effective, and novel by utilizing renewable biomolecules present in ‘Neem leaf extract’. Characterization of the synthesized graphene oxide and NLGOR was performed using UV-Vis, FT-IR, XRD, and Raman spectroscopy, while the imaging was done by TEM, SEM and EDS analysis. Catalytic efficiency of NLGOR was evidenced in the prolific reduction of oxime to equivalent amine in an aqueous medium in an excellent yield (87–93%).

Keywords: Reduced graphene oxide; Neem leaf extract; Oxime reduction; Amine synthesis

Full paper is available at www.springerlink.com.

DOI: 10.1007/s11696-025-04586-4

Chemical Papers 80 (5) 4793–4804 (2026)