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Preparation of 2,4-disubstituted 5-hydroxy-3(2H)-pyridazinones and 2,5-disubstituted 4-hydroxy-3(2H)-pyridazinones

V. Konečný

Research Institute of Agrochemical Technology, 810 04 Bratislava

 

Abstract:  The synthesis of 2,4-disubstituted 5-hydroxy-3(2H)-pyridazinones and 2,5-disubstituted 4-hydroxy-3(2H)-pyridazinones by alkali hydrolysis of 2-substituted 4,5-dihalo-3(2H)-pyridazinones, 2-substituted 4,5-dialkoxy-3(2H)-pyridazinones, 2-substituted 4-alkoxy-5-halo-3(2H)-pyridazinones, 2-substituted 4-halo-5-alkoxy-3(2H)-pyridazinones, 2-substituted 4-halo(alkylthio)-5-alkylthio(halo)-3(2H)-pyridazinones or by the reaction of sodium iodide with 2-substituted 4,5-dialkoxy(dialkylthio)-3(2H)-pyridazinones is described.

Full paper in Portable Document Format: 305a663.pdf

 

Chemical Papers 30 (5) 663–673 (1976)

Monday, June 21, 2021

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