ISSN print edition: 0366-6352
ISSN electronic edition: 1336-9075
Registr. No.: MK SR 9/7

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Color stability of morphine salts

J. Balán and E. Csere

Slovakofarma, Hlohovec

 

Abstract: It has been shown by the effect of N, atm. O, and H2O2 that the discoloration of morphine (I) salts is oxidative, caused by Fe catalysis and org. impurities. Cu has no catalytic effect. I salts can be stabilized by a mixt. of 6% NaHSO3 and 5% of ascorbic acid at pH about 3.0. Solns. of I sulfates are much more stable than of I-HCl.

Full paper in Portable Document Format: 77a409.pdf (in Slovak)

 

Chemical Papers 7 (7) 409–419 (1953)

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